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Description

This regulated necrotic cell death is activated in response to Fas/FasL signaling, CD59 ligation combined with pore formation, mediated by ROS, ceramide, and advanced glycation end products (AGEs) [28]

Domain IV (residues 7051025) consists of -helices and assemble in a "bowl-like" shape

In the study of the protective effect of trehalose on oxidative stress damage in sheep epididymal epididymal cells, it was again found that the upregulation of GPX5 plays a key role (Luan et al., 2021)